Analytical instrumentation
Portable Raman Devices
Raman is a spectroscopic technique that uses the scattering of the monochromatic light from a laser. The laser light interacts with the inter-atomic vibrations of the molecules in the sample, and the resulting shift in energy gives a detailed fingerprint (or Raman shift spectrum) of the sample. Raman spectroscopy does not require physical contact with the sample, making it possible to measure through transparent containers without opening them.
Portable Raman Devices
Raman spectroscopy is widely used today for the identification of materials in the pharmaceutical, chemical and cosmetic industries. Raman combines the advantages of FT-IR (specificity of the spectrum, so easy method development) and NIR (easy analysis – point & shoot).
The TruScan RM is a portable Raman spectrometer used for raw material identification (RMID or Raw Material Identification), finished product inspection, and counterfeit (counterfeit) control.
These lightweight, fast and highly portable Raman analysers are highly specific and allow rapid identification of raw materials and other materials within seconds. Moreover, it is possible to measure through transparent packaging such as plastic bags and glass bottles.
The TruScan handheld Raman analysers are the most widely used portable Raman devices worldwide, and are used by the top 20 pharmaceutical companies.
The TruScan portable Raman devices are GMP compliant and the software is 21 CFR part 11 compliant.
Full Service
Benelux Scientific, as Belgian distributor of the TruScan portable Raman devices, also offers full support:
- preliminary evaluation (checking the list of the customer’s products regarding Raman activity)
- commissioning
- execution of the IQ/OQ
- validation support (extensive database of SOP templates)
training - application support
- technical support
- certification
Applications
Portable Raman is used in a variety of applications:
- identification of pharmaceutical raw materials (pharmaceutical RMID)
- control of medicinal products for counterfeiting
- quality control of active ingredients (API QC)
- nutraceutical RMID
- identification of raw materials for cosmetics
- identification of chemical raw materials and finished products
Types
TruScan G3 handheld Raman analyzer
The TruScan G3 brings laboratory quality to the shop floor, making quality checks quick and easy, reducing costs and increasing productivity.
Key features:
- Versatile accessories for different test situations
- Simple touchscreen operation
- Continuous use with hot swap battery
- Non-destructive testing without opening packaging
- Secure data transfer and regulatory compliance
PAT and QA/QC with the TruTools software
The optional TruTools chemometric software gives users the flexibility to develop customised qualitative and quantitative methods for applications not previously possible with handheld Raman analysers.
Some applications:
- quantitative determination of components
- identification of raw materials with a weak Raman signal
- identification of dosage
- PAT applications such as solvent distillation
- better discrimination against authentic vs counterfeit medicines
- quantitative determination of APIs
The TruScan RM portable Raman analyser with TruTools software becomes a more powerful system, allowing users to develop customised advanced qualitative and quantitative methods for implementation on the device.
Advanced applications that were previously only possible on a lab or benchtop spectrometer can now be performed anywhere in the plant thanks to the TruTools chemometric software.
TruTools uses Solo, a chemometric software package from Eigenvector Research Inc, which allows users to develop their own qualitative and quantitative models that can be implemented on the TruScan RM handheld Raman analyser.
